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Purity:99%
The invention discloses a preparation me...
The present invention relates to novel p...
The invention discloses a compound 2 - [...
3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester
(3S)-3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester
| Conditions | Yield |
|---|---|
|
3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester;
With
copper(l) iodide; (R)-1,1'-binaphthyl-2,2'-phosphoric acid;
In
water; N,N-dimethyl-formamide;
at 50 - 75 ℃;
for 2h;
With
hydrogenchloride; sodium hydroxide;
In
water;
pH=10;
Concentration;
Reagent/catalyst;
Temperature;
|
91.3% |
di-tert-butyl dicarbonate
(3S)-3-(4-aminophenyl)piperidine
(3S)-3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester
| Conditions | Yield |
|---|---|
|
In
dichloromethane;
at -5 - 5 ℃;
|
85% |
|
With
dmap; triethylamine; sodium hydroxide;
In
dichloromethane;
at 20 ℃;
for 8h;
|
12.1 g |
di-tert-butyl dicarbonate
(3S)-3-(4-aminophenyl)piperidinium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate
3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester
tert-butyldicarbonate
tert-butyl (3S)-3-[4-({(1E)-[3-(methoxycarbonyl)-2-nitrophenyl]methylene}amino)phenyl]piperidine-1-carboxylate
(3S)-3-[4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidinium chloride
2-[4-((3S)-(tertbutoxycarbonyl)piperidin-3-yl)phenyl]-2H-indazole-7-carboxylic acid methyl ester
tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate
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