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Purity:99%
The present invention is directed to a m...
A process for preparing xanthine phospho...
1-ethyl-3,7-dihydro-8-[(1R,2R)-(hydroxycyclopentyl)amino]-3-(2-hydroxyethyl)-7-[(3-bromo-4-methoxyphenyl)methyl]-1H-purine-2,6-dione
7-(3-bromo-4-methoxybenzyl)-1-ethyl-8-(((1R,2R)-2-hydroxycyclopentyl)amino)-3-(2-hydroxyethyl)-3,7-dihydro-1H-purine-2,6-dione
| Conditions | Yield |
|---|---|
|
With
tetra(n-butyl)ammonium hydroxide; acetic acid;
In
methanol; ISOPROPYLAMIDE; acetic acid;
at 45 - 85 ℃;
for 8 - 9h;
pH=5 - 6;
|
85% |
C28H44BrN5O5Si
7-(3-bromo-4-methoxybenzyl)-1-ethyl-8-(((1R,2R)-2-hydroxycyclopentyl)amino)-3-(2-hydroxyethyl)-3,7-dihydro-1H-purine-2,6-dione
| Conditions | Yield |
|---|---|
|
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
|
8-amino-7-[(3-bromo-4-methoxyphenyl)methyl]-1-ethyl-3,7-dihydro-3-(2-hydroxyethyl)-1H-purine-2,6-dione
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