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pd_meltingpoint:162-164 °C
Purity:99%
InChI:InChI=1/C6H11NO3/c8-6(9)5-7-1-3-10-4-2-7/h1-5H2,(H,8,9)
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morpholine
bromoacetic acid
morpholin-4-ylacetic acid
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
Inert atmosphere;
|
85.3% |
|
|
|
|
In
tetrahydrofuran;
at 20 ℃;
for 72h;
|
|
|
In
tetrahydrofuran;
at 20 ℃;
for 72h;
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 25 ℃;
Inert atmosphere;
Sealed tube;
|
N-morpholylacetic acid ethyl ester
morpholin-4-ylacetic acid
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
at 95 ℃;
for 16h;
Temperature;
Time;
|
96.3% |
|
With
water;
for 30h;
Heating;
|
87% |
|
With
sodium hydroxide;
In
water;
Heating;
|
65% |
|
With
hydrogenchloride;
In
water;
at 90 ℃;
for 12h;
|
64% |
|
With
water;
for 44h;
Heating / reflux;
|
|
|
N-morpholylacetic acid ethyl ester;
With
potassium hydroxide;
In
water;
at 20 ℃;
With
hydrogenchloride;
In
water;
|
morpholine
4-(morpholinomethyl)morpholine
potassium cyanide
sodium monochloroacetic acid
N-morpholylacetic acid ethyl ester
N-{4-chloro-2-[(2-chloro-phenyl)-(2-hydroxy-1-methyl-ethylimino)-methyl]-phenyl}-2-morpholin-4-yl-acetamide
N-[2-(tert-Butyl-dimethyl-silanyloxy)-3,3,3-trifluoro-1-isopropyl-propyl]-2-[3-(2-morpholin-4-yl-acetylamino)-2-oxo-6-phenyl-2H-pyridin-1-yl]-acetamide
tert-butyl (2S)-{2-(morpholin-4-yl)acetylamino}-3-[3-{4-(pyrimidin-2-ylamino)piperidin-1-yl}benzoylamino]propionate
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