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pd_meltingpoint:107-109 °C
Purity:99%
Embodiments of this invention provide co...
The invention belongs to the field of or...
Fragment-based drug discovery is now wid...
Poly (ADP-ribose) polymerase (PARP) play...
methanol
(S)-2-methylpyrrolidine-2-carboxylic acid
methyl (S)-2-methylpyrrolidine-2-carboxylate monohydrochloride
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
at 0 - 20 ℃;
Inert atmosphere;
|
100% |
|
With
thionyl chloride;
at -5 ℃;
for 24h;
Inert atmosphere;
Reflux;
|
100% |
|
With
thionyl chloride;
at 0 ℃;
Reflux;
|
100% |
|
With
thionyl chloride;
at 0 - 20 ℃;
|
85% |
|
With
hydrogenchloride;
for 3h;
|
|
|
With
thionyl chloride;
at -5 ℃;
for 24h;
Inert atmosphere;
Reflux;
|
0.62 mg |
|
With
thionyl chloride;
for 3h;
|
1.1 g |
|
With
thionyl chloride;
at 0 ℃;
for 4.5h;
Reflux;
|
(3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydropyrrolo[1,2-c]oxazol-1(3H)-one
methyl (S)-2-methylpyrrolidine-2-carboxylate monohydrochloride
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
at 0 - 20 ℃;
for 0.333333h;
Heating / reflux;
|
100% |
|
With
acetyl chloride;
In
methanol;
for 4.5h;
Reagent/catalyst;
Inert atmosphere;
Reflux;
|
48% |
methanol
(3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydropyrrolo[1,2-c]oxazol-1(3H)-one
(S)-2-methylpyrrolidine-2-carboxylic acid
(2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one
(S)-1-tert-butyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate
glycyl-L-2-methylprolyl-L-glutamic acid
(S)-8a-methyloctahydropyrrolo[1,2-a]pyrazine
(R)-methyl 11b-methyl-6-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole-7-carboxylate
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