pd_meltingpoint:194 °C(lit.)
Appearance:crystalline solid
Purity:99%
We describe the preparation of two monom...
Nucleoside analogs represent a class of ...
We have developed a new method, a step-w...
Unnatural nucleosides are attracting int...
2'-deoxyuridine
5-Iodo-2'-deoxyuridine
| Conditions | Yield |
|---|---|
|
With
iodine; silver nitrate;
In
methanol;
at 40 ℃;
for 3h;
|
100% |
|
With
iodine; silver nitrate;
In
methanol;
at 40 ℃;
for 3h;
|
100% |
|
With
sodium azide; Iodine monochloride;
In
acetonitrile;
at 25 ℃;
for 24h;
Product distribution;
Mechanism;
other uracil nucleosides; other halogenation agents; var. temp. and time;
|
96% |
|
With
sodium azide; Iodine monochloride;
In
acetonitrile;
at 25 ℃;
for 24h;
|
96% |
|
With
1-(2-methoxyethyl)-3-methylimidazolium trifluoroacetate; N-iodo-succinimide;
at 60 ℃;
for 0.0666667h;
|
89% |
|
With
ammonium cerium (IV) nitrate; 1-ethylene glycol monomethyl ether-3-methylimidazolium methanesulfonate; lithium iodide;
at 80 ℃;
for 0.166667h;
|
82% |
|
With
ammonium cerium (IV) nitrate; iodine;
In
acetonitrile;
at 50 ℃;
for 4h;
|
81% |
|
With
ammonium cerium(IV) nitrate; lithium iodide;
In
methanol;
at 80 ℃;
|
77% |
|
With
Iodine monochloride;
In
methanol;
at 50 ℃;
for 1.5h;
|
76% |
|
With
iodine;
In
acetonitrile;
Ambient temperature;
electrolysis (Pt electrodes, Ag/Ag+ reference, LiClO4 as supporting electrolyte);
|
75% |
|
With
iodine; silver sulfate;
In
methanol;
for 0.2h;
Ambient temperature;
|
71% |
|
With
iodine; nitric acid;
|
|
|
With
Iodine monochloride; triethylamine;
Yield given. Multistep reaction;
1.) MeOH, 30 min, 2.) 1 h;
|
|
|
With
iodic acid;
|
2'-deoxyuridine
5-iodouracil
5-Iodo-2'-deoxyuridine
uracil
| Conditions | Yield |
|---|---|
|
With
thymidine phosphorylase from Escherichia coli (E.C. 2.4.2.4) immobilized on Sepabeads EC-EP;
In
aq. phosphate buffer;
at 20 ℃;
for 3h;
pH=7.5;
Reagent/catalyst;
Enzymatic reaction;
|
2'-deoxyuridine
3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
5-trimethylstannyl-2'-deoxyuridine
5-iodouracil
2'-deoxyuridine
(E)-2'-deoxy-5-(perfluoropropen-1-yl)uridine
(Z)-2'-deoxy-5-(perfluoropropen-1-yl)uridine
5-Trimethylsilyl-2'-deoxy-β-uridine
CAS：195875-84-4
CAS：4264-93-1
