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488-43-7

  • Product Name:(1-amino-1-deoxy-D-glucitol)
  • Molecular Formula:C6H15NO5
  • Molecular Weight:181.189
  • Appearance:Crystalline solid
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Product Details

pd_meltingpoint:126-128°C (dec.)

Appearance:Crystalline solid

Purity:99%

Cosmetics Grade (1-amino-1-deoxy-D-glucitol) 488-43-7 For Sale with Good Price

  • Molecular Formula:C6H15NO5
  • Molecular Weight:181.189
  • Appearance/Colour:Crystalline solid 
  • Vapor Pressure:1.78E-13mmHg at 25°C 
  • Melting Point:126-128°C (dec.) 
  • Refractive Index:-7 ° (C=10, H2O) 
  • Boiling Point:530.7 °C at 760 mmHg 
  • PKA:11.96±0.35(Predicted) 
  • Flash Point:274.7 °C 
  • PSA：127.17000 
  • Density:1.506 g/cm3 
  • LogP:-2.91870 

D-GLUCAMINE(Cas 488-43-7) Usage

Purification Methods

Crystallise glucamine from MeOH or aqueous MeOH and store it in a CO2-free atmosphere. For the N-methylglucamine derivative see below. [Holly et al. J Am Chem Soc 72 5461 1950, Karrer et al. Helv Chim Acta 20 83 1937.]

InChI:InChI=1/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4+,5+,6+/m0/s1

488-43-7 Relevant articles

The effect of MR1 ligand glyco-analogues on mucosal-associated invariant T (MAIT) cell activation

Braganza, Chriselle D.,Shibata, Kensuke,Fujiwara, Aisa,Motozono, Chihiro,Sonoda, Koh-Hei,Yamasaki, Sho,Stocker, Bridget L.,Timmer, Mattie S. M.

supporting information, p. 8992 - 9000 (2019/10/28)

Mucosal-associated invariant T (MAIT) ce...

Synthesis and biological evaluation of new carbohydrate-substituted indenoisoquinoline topoisomerase I inhibitors and improved syntheses of the experimental anticancer agents indotecan (LMP400) and indimitecan (LMP776)

Beck, Daniel E.,Agama, Keli,Marchand, Christophe,Chergui, Adel,Pommier, Yves,Cushman, Mark

, p. 1495 - 1512 (2014/03/21)

Carbohydrate moieties were strategically...

ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS

-

Page/Page column 46-47, (2012/12/13)

The invention described herein pertains ...

Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase i inhibitors: Investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity

Peterson, Katherine E.,Cinelli, Maris A.,Morrell, Andrew E.,Mehta, Akhil,Dexheimer, Thomas S.,Agama, Keli,Antony, Smitha,Pommier, Yves,Cushman, Mark

, p. 4937 - 4953 (2011/09/21)

The DNA-relaxing enzyme topoisomerase I ...

488-43-7 Process route

D-glucose
50-99-7

D-glucose

1-Amino-1-deoxy-D-glucitol
488-43-7

1-Amino-1-deoxy-D-glucitol

Conditions
Conditions Yield
With ammonium hydroxide; ammonium acetate; sodium cyanoborohydride; In ethanol; Reflux;
77%
With ammonia; nickel; at 85 ℃; under 102971 Torr; Hydrogenation;
With ammonia; water; nickel; at 90 - 120 ℃; under 73550.8 Torr; Hydrogenation;
With methanol; ammonia; nickel; at 100 - 115 ℃; under 114004 Torr; Hydrogenation;
Multi-step reaction with 2 steps
1: H2O / anschliessendes Hydrieren nach Zusatz von Methanol an Platin
2: palladium/charcoal; ethanol / Hydrogenation
With palladium on activated charcoal; ethanol; water;
Multi-step reaction with 2 steps
1.1: hydroxylamine hydrochloride; sodium methylate / ethanol / 20 °C
1.2: 70 °C
2.1: platinum(IV) oxide; hydrogen; acetic acid / 20 °C / 1810.07 - 2327.23 Torr
With platinum(IV) oxide; hydroxylamine hydrochloride; hydrogen; sodium methylate; acetic acid; In ethanol;
Multi-step reaction with 2 steps
1: hydroxylamine hydrochloride; sodium methylate / 70 °C
2: platinum(IV) oxide; hydrogen; acetic acid / water / 48 h / 2068.65 Torr
With platinum(IV) oxide; hydroxylamine hydrochloride; hydrogen; sodium methylate; acetic acid; In water;
With ammonia; water; nickel; at 90 - 120 ℃; under 73550.8 Torr; Hydrogenation;
With water; nickel; hydrazine; at 100 ℃; under 73550.8 Torr; Hydrogenation;
D-glucose oxime
608-81-1

D-glucose oxime

1-Amino-1-deoxy-D-glucitol
488-43-7

1-Amino-1-deoxy-D-glucitol

Conditions
Conditions Yield
With platinum(IV) oxide; hydrogen; acetic acid; at 20 ℃; under 1810.07 - 2327.23 Torr;
With platinum(IV) oxide; hydrogen; acetic acid; In water; for 48h; under 2068.65 Torr;

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