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Purity:99%
Since its discovery in 1998, the orexin ...
Bridged compounds of Formula (I) and For...
Fused compounds of Formula (I) and Formu...
A selective and scalable synthesis of 2-...
carbon dioxide
2-(2-iodo-4-methoxyphenyl)-2H-[1,2,3]triazole
5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid
| Conditions | Yield |
|---|---|
|
2-(2-iodo-4-methoxyphenyl)-2H-[1,2,3]triazole;
With
isopropylmagnesium chloride;
In
tetrahydrofuran;
at 0 ℃;
carbon dioxide;
In
tetrahydrofuran;
at -20 ℃;
for 0.5h;
|
87% |
|
2-(2-iodo-4-methoxyphenyl)-2H-[1,2,3]triazole;
With
isopropylmagnesium chloride;
In
tetrahydrofuran;
carbon dioxide;
In
tetrahydrofuran;
for 0.5h;
|
87% |
|
2-(2-iodo-4-methoxyphenyl)-2H-[1,2,3]triazole;
With
isopropylmagnesium chloride;
In
tetrahydrofuran;
at 0 ℃;
carbon dioxide;
In
tetrahydrofuran;
at -20 ℃;
for 0.5h;
|
87% |
5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid potassium salt
5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
tert-butyl methyl ether; water;
Reagent/catalyst;
Solvent;
|
61% |
1,2,3-triazole
2-iodo-5-methoxybenzoic acid
1 ,2,3-Triazole
carbon dioxide
N-ethyl-N-{2-[3-(5-fluoropyridin-2-yl)-1H-pyrazol-1-yl]ethyl}-5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzamide
(S)-(2-(6-chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
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