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1353016-71-3

  • Product Name:DBCO-NHS ester
  • Molecular Weight:402.406
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Product Details

Purity:99%

Buy high quality and low price DBCO-NHS ester 1353016-71-3 now

  • Molecular Formula:C23H18N2O5
  • Molecular Weight:402.406
  • Boiling Point:670.2±65.0 °C(Predicted) 
  • PKA:-0.23±0.20(Predicted) 
  • Density:1.43±0.1 g/cm3(Predicted) 

1353016-71-3 Relevant articles

ANTIBODY-DRUG CONJUGATES CONTAINING AN ANTI-MESOTHELIN ANTIBODY AND USES THEREOF

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Paragraph 0133-0134; 0161-0164, (2021/12/29)

The present disclosure provides an immun...

STEROIDS AND PROTEIN-CONJUGATES THEREOF

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Paragraph 0637, (2018/05/27)

Described herein protein steroid conjuga...

NOVEL LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES

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Paragraph 0050, (2015/10/28)

Cell binding agent-drug conjugates compr...

Strain-promoted "click" modification of a mesoporous metal-organic framework

Liu, Chong,Li, Tao,Rosi, Nathaniel L.

, p. 18886 - 18888 (2013/01/15)

Strain-promoted "click" chemistry is use...

1353016-71-3 Process route

1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

4-{2-azatricyclo[10.4.0.0<SUP>4</SUP>'<SUP>9</SUP>]hexadeca-1<sup>(16)</sup>,4<sup>(9)</sup>,5,7,12,14-hexaen-10-yn-2-yl}-4-oxobutanoic acid
1353016-70-2

4-{2-azatricyclo[10.4.0.04'9]hexadeca-1(16),4(9),5,7,12,14-hexaen-10-yn-2-yl}-4-oxobutanoic acid

4-{2-azatricyclo[10.4.0.0<SUP>4</SUP>'<SUP>9</SUP>]hexadeca-1<sup>(12)</sup>,4<sup>(9)</sup>,5,7,13,15-hexaen-10-yn-2-yl}-4-oxobutanoic acid
1353016-71-3

4-{2-azatricyclo[10.4.0.04'9]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl}-4-oxobutanoic acid

Conditions
Conditions Yield
With N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
82%
With N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
With N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 3h;
With N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 3h;
N-iodo-succinimide
516-12-1

N-iodo-succinimide

4-{2-azatricyclo[10.4.0.0<SUP>4</SUP>'<SUP>9</SUP>]hexadeca-1<sup>(16)</sup>,4<sup>(9)</sup>,5,7,12,14-hexaen-10-yn-2-yl}-4-oxobutanoic acid
1353016-70-2

4-{2-azatricyclo[10.4.0.04'9]hexadeca-1(16),4(9),5,7,12,14-hexaen-10-yn-2-yl}-4-oxobutanoic acid

4-{2-azatricyclo[10.4.0.0<SUP>4</SUP>'<SUP>9</SUP>]hexadeca-1<sup>(12)</sup>,4<sup>(9)</sup>,5,7,13,15-hexaen-10-yn-2-yl}-4-oxobutanoic acid
1353016-71-3

4-{2-azatricyclo[10.4.0.04'9]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl}-4-oxobutanoic acid

Conditions
Conditions Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl acetamide;

1353016-71-3 Upstream products

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    6066-82-6

    1-hydroxy-pyrrolidine-2,5-dione

  • 1353016-70-2
    1353016-70-2

    4-{2-azatricyclo[10.4.0.04'9]hexadeca-1(16),4(9),5,7,12,14-hexaen-10-yn-2-yl}-4-oxobutanoic acid

  • 23112-88-1
    23112-88-1

    dibenzo[b,f]azocin-6(5H)-one

  • 23194-93-6
    23194-93-6

    2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4(9),5,7,10,12,14-heptene

1353016-71-3 Downstream products

  • 1364319-93-6
    1364319-93-6

    C27H23FN4O3

  • 1364319-94-7
    1364319-94-7

    methyl 4-(1-(4-fluorophenyl)-1H-dibenzo[b,f][1,2,3]triazolo[4,5-d]azocin-8(9H)-yl)-4-oxobutanoate

  • 1537170-85-6
    1537170-85-6

    1-(4-{2-azatricyclo[10.4.0.04,9]hexadeca-1(12),4(9),5,7,13,15-hexane-10-yn-2-yl}-4-oxobutanamido)-3,6,9,12-tetraoxapentadecan-15-oic acid

  • 1427004-19-0
    1427004-19-0

    2,5-dioxopyrrolidin-1-yl 1-(4-{2-azatricyclo[10.4.0.04,9]hexadeca-1(12),4(9),5,7,13,15-hexane-10-yn-2-yl}-4-oxobutanamido)-3,6,9,12-tetraoxapentadecan-15-oate

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