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110117-71-0

  • Product Name:(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine
  • Molecular Formula:C11H20N2O2
  • Molecular Weight:212.292
  • Appearance:white solid
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Product Details

Appearance:white solid

Purity:99%

Cost-effective and customizable (R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine 110117-71-0 in stock

  • Molecular Formula:C11H20N2O2
  • Molecular Weight:212.292
  • Appearance/Colour:white solid 
  • Vapor Pressure:0.00587mmHg at 25°C 
  • Refractive Index:1.499 
  • Boiling Point:282 °C at 760 mmHg 
  • PKA:6.74±0.60(Predicted) 
  • Flash Point:102.9 °C 
  • PSA：43.18000 
  • Density:1.06 g/cm3 
  • LogP:0.76580 

(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine(Cas 110117-71-0) Usage

InChI:InChI=1/C11H20N2O2/c1-5-14-9-7-12-11(15-6-2)10(13-9)8(3)4/h8,10H,5-7H2,1-4H3/t10-/m1/s1

110117-71-0 Relevant articles

Microwave-assisted synthesis of the Sch?llkopf chiral auxiliaries: (3S)- and (3R)-3,6-dihydro-2,5-diethoxy-3-isopropyl-pyrazine

Carlsson, Anna-Carin,Jam, Fariba,Tullberg, Marcus,Pilotti, ?ke,Ioannidis, Panos,Luthman, Kristina,Gr?tli, Morten

, p. 5199 - 5201 (2006)

A practical and efficient methodology fo...

Sila-substitution of the α-amino acid proline: Synthesis of rac- and (R)-4,4-Dimethyl-4-sila-proline ethyl ester

Handmann, Vera Iris,Merget, Markus,Tacke, Reinhold

, p. 133 - 138 (2000)

In context with studies on silicon-conta...

Stereostructure Clarifying Total Synthesis of the (Polyenoyl)tetramic Acid Militarinone B. A Highly Acid-Labile N-Protecting Group for Amides ?

Drescher, Christian,Brückner, Reinhard

supporting information, p. 6194 - 6199 (2021/08/18)

The 5S, 8′R, and 10′R configurations of ...

Structure-Enabled Discovery of a Stapled Peptide Inhibitor to Target the Oncogenic Transcriptional Repressor TLE1

McGrath, Sally,Tortorici, Marcello,Drouin, Ludovic,Solanki, Savade,Vidler, Lewis,Westwood, Isaac,Gimeson, Peter,Van Montfort, Rob,Hoelder, Swen

supporting information, p. 9577 - 9584 (2017/07/22)

TLE1 is an oncogenic transcriptional co-...

The synthesis of methylated, phosphorylated, and phosphonated 3′-aminoacyl-tRNASec mimics

Rigger, Lukas,Schmidt, Rachel L.,Holman, Kaitlyn M.,Simonovic, Miljan,Micura, Ronald

supporting information, p. 15872 - 15878 (2014/04/03)

The twenty first amino acid, selenocyste...

110117-71-0 Process route

triethyloxonium fluoroborate
368-39-8

triethyloxonium fluoroborate

(R)-3-(1-methylethyl)-piperazine-2,5-one
143673-66-9

(R)-3-(1-methylethyl)-piperazine-2,5-one

(2R)-3,6-diethoxy-2-isopropyl-2,5-dihydropyrazine
110117-71-0

(2R)-3,6-diethoxy-2-isopropyl-2,5-dihydropyrazine

Conditions
Conditions Yield
92%
In dichloromethane; at 20 ℃; for 120h;
92%
In dichloromethane; at 20 ℃;
90%
In dichloromethane; at 20 ℃; for 120h; Inert atmosphere;
90%
In dichloromethane; at 20 ℃; for 96h;
90%
In dichloromethane; at 20 ℃; for 72h;
77%
In dichloromethane; at 25 ℃; for 96h;
77%
boron trifluoride diethyl etherate
109-63-7

boron trifluoride diethyl etherate

(2S)-isopropylpiperazine-3,6-dione
16944-60-8

(2S)-isopropylpiperazine-3,6-dione

(2R)-3,6-diethoxy-2-isopropyl-2,5-dihydropyrazine
110117-71-0

(2R)-3,6-diethoxy-2-isopropyl-2,5-dihydropyrazine

Conditions
Conditions Yield
In dichloromethane; at 20 ℃; for 48h;

110117-71-0 Upstream products

  • 143673-66-9
    143673-66-9

    (R)-3-(1-methylethyl)-piperazine-2,5-one

  • 106-89-8
    106-89-8

    epichlorohydrin

  • 368-39-8
    368-39-8

    triethyloxonium fluoroborate

  • 850312-86-6
    850312-86-6

    ((R)-2-tert-butoxycarbonylamino-3-methylbutyrylamino)-acetic acid methyl ester

110117-71-0 Downstream products

  • 110117-72-1
    110117-72-1

    (R)-3,6-Diethoxy-2-isopropyl-5-[5-(4-methoxy-benzylsulfanyl)-3-methyl-3H-imidazol-4-ylmethyl]-2,5-dihydro-pyrazine

  • 202199-21-1
    202199-21-1

    (1R,1S,2S,3S,4'R,12R)-2-benzyloxy-3,12-di(tert-butyldimethylsiloxy)-1-(3',6'-diethoxy-4'-(isopropyl)-1'H,4'H-2',5'-diazyl)-octadec-4-ene-1-ol

  • 202199-20-0
    202199-20-0

    (1S,1S,2S,3S,4'R,12R)-2-benzyloxy-3,12-di(tert-butyldimethylsiloxy)-1-(3',6'-diethoxy-4'-(isopropyl)-1'H,4'H-2',5'-diazyl)-octadec-4-ene-1-ol

  • 202199-22-2
    202199-22-2

    (1R,1R,2S,3S,4'S,12R)-2-benzyloxy-3,12-di(tert-butyldimethylsiloxy)-1-(3',6'-diethoxy-4'-(isopropyl)-1'H,4'H-2',5'-diazyl)-octadec-4-ene-1-ol

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