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763113-22-0

  • Product Name:Olaparib
  • Molecular Formula:C24H23FN4O3
  • Molecular Weight:434.47
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Product Details

Purity:99%

Quality Factory Supply 99% Pure Olaparib 763113-22-0 with Efficient Delivery We supply high quality Olaparib (CAS 763113-22-0), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Olaparib ?

Olaparib is , while it's Molecular Formula is C24H23FN4O3. Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.[Cayman Chemical]

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