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Purity:99%
Cost-effective and customizable ITF2357 732302-99-7 for sale We supply high quality Givinostat (ITF2357) (CAS 732302-99-7), in stock, factory directly supply to clients, lower prices, more competitiveness.
Givinostat (ITF2357) is , while it's Molecular Formula is C24H27N3O4.HCl.H2O. Givinostat hydrochloride hydrate has been used as a histone deacetylase inhibitor to test its effect on the human immunodeficiency virus reactivation in CD4+ T-cell model.
The CAS number of Givinostat (ITF2357) is 732302-99-7.
More information of Givinostat (ITF2357) 732302-99-7 are:
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Synonyms |
ITF2357;ITF2357 (Givinostat);N-[4-[(Hydroxyamino)carbonyl]phenyl]carbamic acid [6-[(diethylamino)methyl]-2-naphthalenyl]methyl ester hydrochloride hydrate;(6-((diethylamino)methyl)naphthalen-2-yl)methyl 4-(hydroxycarbamoyl)phenylcarbamate hydrochloride hydrate |
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CAS Number |
732302-99-7 |
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Molecular Formula |
C24H27N3O4.HCl.H2O |
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Molecular Weight |
475.97 |
|
PSA |
100.13000 |
|
LogP |
5.75090 |
Givinostat (ITF2357) is a histone deacetylase (HDAC) inhibitor with a potent IC50 of 7.5-16 nM. It is a pharmaceutical compound that modulates the acetylation of histone proteins, which play a crucial role in the regulation of gene expression. Givinostat has shown potential in the treatment of various diseases by targeting the epigenetic mechanisms involved in their pathogenesis.
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