Your Location：Home >Products >API >90357-06-5

90357-06-5

  • Product Name:Bicalutamide
  • Molecular Formula:C18H14F4N2O4S
  • Molecular Weight:430.38
  • Appearance:off-white crystalline solid
Inquiry

Product Details

pd_meltingpoint:191-193 °C

Appearance:off-white crystalline solid

Purity:99%

Cosmetics Grade Bicalutamide 90357-06-5 For Sale with Good Price We supply high quality Bicalutamide (CAS 90357-06-5), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Bicalutamide ?

Bicalutamide is off-white crystalline solid, while it's Molecular Formula is C18H14F4N2O4S. Bicalutamide (CDX) has been used as an androgen receptor (AR) antagonist in prostate, bladder cancer cell lines and human fetal skeletal muscle cells. It has also been used as a supplement in RPMI 1640 for culturing androgen-independent LNCaP (LNCaP-AI) cell line.

What is the CAS number for Bicalutamide ?

The CAS number of Bicalutamide is 90357-06-5.

More information of Bicalutamide 90357-06-5 are:

Synonyms

 (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide;Casodex;Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)-;Bicalutamide (JAN/USP);Casodex (TN);(±)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-methyl-[(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide;N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide;Bicalutamide [USAN:BAN:INN];ICI 176334;Propanamide,N-[4-cyano-3-(trifluoromethyl)- phenyl]-3-[(4-fluorophenyl)sulfonyl]-2- hydroxy-2-methyl-;

CAS Number

 90357-06-5

Molecular Formula

 C18H14F4N2O4S

Molecular Weight

 430.38

Density

 1.52 g/cm3

Melting Point

 191-193 °C

Boiling Point

 650.3 °C at 760 mmHg

Flash Point

 347.1 °C

HS CODE

 29242995

PSA

 115.64000

LogP

 4.03338

Pka

 11.49±0.29(Predicted)

What is Bicalutamide (90357-06-5) used for?

Bicalutamide was launched in the United Kingdom, its first worldwide market, for the treatment of advanced prostate cancer in combination with an LHRH analog or surgical castration. A non-steroidal, peripherally selective antiandrogen, bicalutamide inhibits the action of dihydrotestosterone and testosterone at target sites by competitive binding to the cytosolic androgen receptor. It was reportedly well tolerated with no significant cardiovascular and metabolic side effects due to the benefit of lacking any steroid activity. The efficacy of bicalutamide as a monotherapy has been demonstrated clinically. Promising response rates were also reported in treating colorectal, breast, pancreas and non-small cell lung cancers.

InChI:InChI=1/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/t17-/m1/s1

Articles related to Bicalutamide:

Article

Source

Preparation method of (R)-bicalutamide intermediate

-

Paragraph 0068-0070, (2021/04/21)

Preparation of a novel bridged bis(β-cyclodextrin) chiral stationary phase by thiol-ene click chemistry for enhanced enantioseparation in HPLC

Gong, Bolin,Guo, Siyu,Zhang, Ning

, p. 35754 - 35764 (2021/12/02)

How to get the best price on Bicalutamide?

Zibo Yurui Biotechnology Co., Ltd is a quality supplier and manufacturer of Bicalutamide . You can buy high quality, low price Bicalutamide 90357-06-5 here. Contact us.

Relevant Products

  • Friend Links:
  • Tel: +86 13645336065Email: zhang@yuruibiotech.com
  • Address: 500 meters north of the intersection of Dongsi Road and Zihe Avenue (right side), Economic Development Zone, Zibo City, Shandong Province, China
Copyright @2009-2026 Zibo Yurui Biotechnology Co., Ltd.