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Purity:99%
The present invention relates to novel c...
?(R)-3-methylpiperazin-2-one
2,4-Dimethoxybenzaldehyde
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
| Conditions | Yield |
|---|---|
|
With
sodium tris(acetoxy)borohydride; acetic acid;
In
acetonitrile;
at 20 ℃;
Inert atmosphere;
|
98% |
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
triethyloxonium fluoroborate
(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine
| Conditions | Yield |
|---|---|
|
With
sodium carbonate;
In
dichloromethane;
at 15 - 20 ℃;
for 0.75h;
Inert atmosphere;
|
67% |
|
With
sodium carbonate;
In
dichloromethane;
at 15 - 21 ℃;
for 0.75h;
Inert atmosphere;
|
67% |
|
With
sodium carbonate;
In
dichloromethane;
at 20 ℃;
for 1h;
Inert atmosphere;
|
48% |
|
With
sodium carbonate;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
|
48% |
|
With
sodium carbonate;
In
dichloromethane;
|
?(R)-3-methylpiperazin-2-one
2,4-Dimethoxybenzaldehyde
(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine
(R)-4-(7-(2,4-dimethoxybenzyl)-8-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-2-methylthiazole
(R)-(8-methyl-3-(2-methylthiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)(4-(thiophen-2-yl)phenyl)methanone
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