1383146-20-0

  • Product Name:(R)-4-(2,4-diMethoxybenzyl)-3-Methylpiperazin-2-one
  • Molecular Formula:C14H20N2O3
  • Molecular Weight:264.324
Inquiry

Product Details

Purity:99%

Factory supply good quality (R)-4-(2,4-diMethoxybenzyl)-3-Methylpiperazin-2-one 1383146-20-0 with stock

  • Molecular Formula:C14H20N2O3
  • Molecular Weight:264.324
  • Boiling Point:436.1±45.0 °C(Predicted) 
  • PKA:15.07±0.40(Predicted) 
  • PSA:54.29000 
  • Density:1.118±0.06 g/cm3(Predicted) 
  • LogP:1.23790 

1383146-20-0 Relevant articles

NOVEL CHIRAL N-ACYL-5,6,7,(8-SUBSTITUTED)-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR MEDIATED DISORDERS AND CHIRAL SYNTHESIS THEREOF

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Page/Page column 136-137, (2013/04/24)

The present invention relates to novel c...

1383146-20-0 Process route

?(R)-3-methylpiperazin-2-one
922178-61-8

?(R)-3-methylpiperazin-2-one

2,4-Dimethoxybenzaldehyde
613-45-6

2,4-Dimethoxybenzaldehyde

(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
1383146-20-0

(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one

Conditions
Conditions Yield
With sodium tris(acetoxy)borohydride; acetic acid; In acetonitrile; at 20 ℃; Inert atmosphere;
98%
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
1383146-20-0

(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one

triethyloxonium fluoroborate
368-39-8

triethyloxonium fluoroborate

(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine
1429560-52-0

(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Conditions
Conditions Yield
With sodium carbonate; In dichloromethane; at 15 - 20 ℃; for 0.75h; Inert atmosphere;
67%
With sodium carbonate; In dichloromethane; at 15 - 21 ℃; for 0.75h; Inert atmosphere;
67%
With sodium carbonate; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;
48%
With sodium carbonate; In dichloromethane; at 20 ℃; Inert atmosphere;
48%
With sodium carbonate; In dichloromethane;

1383146-20-0 Upstream products

  • 922178-61-8
    922178-61-8

    ?(R)-3-methylpiperazin-2-one

  • 613-45-6
    613-45-6

    2,4-Dimethoxybenzaldehyde

1383146-20-0 Downstream products

  • 1429560-52-0
    1429560-52-0

    (R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

  • 1429607-62-4
    1429607-62-4

    (R)-4-(7-(2,4-dimethoxybenzyl)-8-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-2-methylthiazole

  • 1429556-99-9
    1429556-99-9

    (R)-(8-methyl-3-(2-methylthiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)(4-(thiophen-2-yl)phenyl)methanone

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